Calibrators & Controls

Reagents

HUMAN's reagents provide high-quality and reliable solutions tailored to meet diverse laboratory needs. Our range includes multipurpose clinical chemistry assays for manual and automated testing, offering precision in the detection of enzymes, substrates/metabolites, proteins, electrolytes, and trace elements detection. Our products ensure long-term stability and high accuracy. Each reagent kit includes necessary calibrators and standards, facilitating ease of use. With a commitment to innovation, HUMAN ensures that laboratories receive efficient, cost-effective diagnostic solutions that enhance the accuracy and reliability of their results.

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  • Clinical Chemistry Reagents
  • ELISA
  • Rapid Screening Tests
  • Rheumatology
  • Urinalysis

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Lactate dehydrogenase measurements are used for diagnosis and therapy control of liver diseases such as acute viral hepatitis, cirrhosis, malignant liver diseases, myocardial infarction, tumors of the lung or kidneys, pulmonary embolism and hemolytic anemia.

Enzymatic UV test for the quantitative determination of lactate dehydrogenase in human serum and plasma.
LDL cholesterol (LDL-c) is an independent risk factor for coronary vascular disease (CHD). Epidemiological studies have shown the importance of LDL-c levels for the identification of high risk patients. HDL cholesterol (HDL-c) is regarded a protecting lipid component against coronary vascular disease (CHD). Together with HDL cholesterol LDL cholesterol has a high diagnostic value to estimate the individual risk for CHD.

Homogeneous enzymatic color assay for the quantitative determination of LDL cholesterol in human serum and plasma.
Lipase activity measurements are used primarily to investigate pancreatic disorders, usually pancreatitis. Indications for lipase measurements are detection and exclusion of acute pancreatitis (in acute upper quadrant abdominal pain), chronic (relapsing) pancreatitis, obstruction of the pancreatic duct and detection of pancreatic involvement in abdominal diseases.

Enzymatic colorimetric test for the quantitative determination of lipase in human serum and plasma.
Lp(a) is a risk factor for coronary vascular disease that is independent of all other lipid parameters. The Lp(a) concentration in blood varies from almost undetectable levels to more than 100 mg/dl. Differences in Lp(a) levels are genetically determined and will not be much influenced by lifestyle. The presence of high Lp(a) levels in serum is a significant marker for an increased risk of atherosclerosis and coronary vascular disease, especially when Lp(a) and LDL-c concentrations are elevated simultaneously.

Latex enhanced immunoturbidimetric test for the quantitative determination of lipoprotein (a) in human serum.
Quantitative determination of luteinizing hormone (LH)
​​​​​​​Remark: WHO Calibration
Magnesium measurements are used in the diagnosis and treatment of hypo- and hypermagnesemia. When making clinical assessment of magnesium levels the calcium levels should also be considered. The best-defined manifestation of magnesium deficiency is impairment of neuromuscular function e.g. hyperirritability, tetany, convulsions, and electrocardiographic changes.

Hypomagnesemia: Observed in diabetes, chronic alcoholism, forced diuresis, hyperthyroidism, hypoparathyroidism, hypocalcemia, malabsorption and acute pancreatitis.

Hypermagnesemia: Increased serum magnesium levels have been found in cases of renal failure, dehydration, severe diabetic ketoacidosis and Addison's disease.

Colorimetric test for the quantitative determination of magnesium in human serum and plasma (no EDTA plasma).
Qualitative determination of IgG or IgM antibodies to measles virus
Microalbuminuria is considered a clinically important indicator of deteriorating renal function in diabetic subjects and regular screening is valuable in monitoring these patients. Prospective studies have demonstrated that increased urinary albumin excretion precedes and is highly predictive of diabetic nephropathy, end stage renal disease, and proliferative retinopathy in type I diabetes. In patients with type II diabetes increased urinary albumin excretion is an independent predictor of progressive renal disease, atherosclerotic disease and cardiovascular mortality. Increased urinary albumin excretion, both independently and in conjunction with hyperinsulinemia, identifies a group of nondiabetic subjects at increased risk of coronary vascular disease.

Immunoturbidimetric test for the quantitative determination of mircoalbumin in collected urine or random midstream urine.
Quantitative determination of IgG antibodies to myeloperoxidase.
Calibration: 2.5 / 7.4 / 22.2 / 66.7 / 200 U/ml Cut-off: 10 U/ml
Qualitative determination of myositis IgG antibodies.

Internal function and cut-off control
Quantitative determination of IgG antibodies to nucleosomes.
Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Immunochromatographic rapid test for the qualitative detection of faecal occult blood in human stool
Pancreatic amylase activity measurements in serum and urine are mainly applied for the diagnosis of pancreatic disorders as well as for detecting the development of complications. As pancreatic and salivary amylase show a structural homology of 97%, the only method to distinguish is to use an assay based on monoclonal antibodies to inhibit the salivary enzyme. The amylase in the blood is eliminated through the kidneys and excreted into the urine, therefore, elevated serum activity is reflected in the rise of urinary amylase activity. For confirmation of an acute pancreatitis an additional measurement of lipase is recommended.

Enzymatic colorimetric test for the quantitative determination of pancreatic amylase in human serum, plasma and urine.
Quantitative determination of IgG / IgA / IgM antibodies to phosphatidylethanolamine.
Calibration: 6.25 / 12.5 / 25 / 50 / 100 U/ml Cut-off: 15 U/ml
Determination of antibodies to phosphatidylserine
Quantitative determination of IgG / IgM antibodies to phospholipids.
Calibration: 6 / 12.5 / 25 / 50 / 100 U/ml Cut-off: 15-25 U/ml
Inorganic phosphorus (PHOS, PO3) is measured for diagnosis and therapy control of various disorders such as bone diseases, chronic kidney disease, dialysis patients, kidney stones, after thyroid surgery, diseases of the parathyroid gland, chronic alcoholism, in intensive care (parenteral nutrition, ventilated patients), suspected Vit D deficiency, muscle weakness and bone pain.

UV test for quantitative determination of inorganic phosphate in human serum.
Potassium measurements are used in the diagnosis and treatment of hypokalemia (chronic ingestion of diuretics and laxatives, with/without disorders of the acid-base balance), hyperkalemia (overadministration of potassium, acidosis, or crush injuries), renal failure, Addison`s disease or other diseases involving electrolyte imbalance.

Photometric tests for the quantitative determination of potassium in human serum and heparinised plasma.
Quantitative determination of IgG antibodies to proteinase 3.
Calibration: 2.5 / 7.4 / 22.2 / 66.7 / 200 U/ml Cut-off: 10 U/ml

Quantitative determination of human chorionic gonadotropin (hCG) Remark: WHO Calibration

Quantitative determination of progesterone
Quantitative determination of prolactin (PRL)
​​​​​​​​​​​​​​Remark: WHO Calibration

Quantitative determination of total prostate specific antigen Remark: WHO Calibration

Quantitative determination of IgG / IgA / IgM antibodies to prothrombin.
Calibration: 6.25 / 12.5 / 25 / 50 / 100 U/ml Cut-off: 30 U/ml
Quantitative determination of IgG antibodies to RA33.
Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Quantitative determination of IgM antibodies to rheumatoid factor.
Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 15 IU/ml

Qualitative determination of IgG antibodies to rubella virus
Remark: Rubella IgG (WHO calibration)

Determination of antibodies to ß2-Glycoprotein 1
Qualitative determination of antibodies to salmonella.
Quantitative / qualitative determination of IgG antibodies to Scl70.
Calibration: 12.5/25/50/100/200 U/ml Cut-off: 25 U/ml
Latex slide test for serum.
Quantitative / qualitative determination of IgG antibodies to SmD.
Calibration: 12.5 /25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Sodium measurements are used in the diagnosis and treatment of disturbances of fluid and electrolyte balance, e.g. due to a loss of water or salt, and other serum electrolytes deviating from their reference interval by polyuric-polydypsic syndromes and impaired thirst, renal diseases, hypertension, disorders of the acid-base balance, some endocrine diseases, edema, excessive sodium intake.

Colorimetric tests for the quantitative determination of sodium in human serum and heparinized plasma.
Quantitative / qualitative determination of IgG antibodies to SS-A/Ro.
Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Quantitative / qualitative determination of IgG antibodies to SS-B/La.
Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Qualitative determination of antibodies to Treponema pallidum
Quantitative determination of testosterone
Quantitative determination of Thyrotropin.
The iron and total iron binding capacity (TIBC) levels are influenced by changes in iron intake, absorption, storage, and release mechanisms. Such changes are indicative of a wide range of dysfunctions including anemias, nephrosis, cirrhosis and hepatitis. Iron and TIBC measurements are interrelated parameters for the diagnosis of the iron status.

Saturation and absorbant reagents for sample preparation for the determination of total iron binding capacity (TIBC) in human serum or heparinised plasma.
Total protein (TP) is a major component of blood and the sum of all circulating proteins. Total protein is measured for diagnosis and therapy control of a variety of diseases involving liver, kidney or bone marrow as well as other metabolic and nutritional disorders. Hypoproteinemia may be caused by abnormal synthesis, protein malnutrition, protein malabsorption, protein loss and after infusions. Hyperproteinemia may be caused by monoclonal gammopathy, severe chronic inflammatory and autoimmune processes.

Colorimetric test for the quantitative determination of total protein in human serum and plasma.
Quantitative determination of total thyroxine (T4)
Quantitative determination of total triiodothyronine (T3)
Qualitative determination of IgG or IgM (μ-capture) antibodies to Toxoplasma gondii
Remark: Toxo IgG (WHO calibration)
Transferrin is the principle plasma protein for the transport of iron. Transferrin is a negative acute phase reactant and will decrease during any inflammatory state or malignancy. Increased levels of transferrin are found in iron deficiency, pregnancy, oestrogen administration and lipoidal nephrosis. Decreased levels may be encountered in hereditary deficiencies, testosterone administration, infection, acute inflammation, some forms of nephrosis, tumors, haemochromatosis, acute malaria and malnutrition.

Immunoturbidimetric test for the quantitative determination of transferrin in human serum.
The measurement of triglycerides (TG) is used for diagnosis of primary and secondary hyperlipoproteinemias, primary and secondary prevention of coronary vascular disease (CHD), risk marker of metabolic syndrom, LDL-c calculation using the Friedewald formula as well as control of dietary and medical lipid lowering.

Enzymatic colorimetric test for the quantitative determination of triglycerides in human serum and plasma.
Test for the triage of patients suspected for myocardial infarction in locations without access to particle-based chemiluminescent Troponin immunoassays.

Immunochromatographic 1-step test for cardiac troponin I (cTnI).

Detection limit: 0.5 ng/ml.
Quantitative / qualitative determination of IgG antibodies to U1-snRNP.

Calibration: 12.5/25/50/100/200 U/ml

Cut-off: 25 U/ml
Urea (UREA, BUN) measurements are used in the diagnosis, differential diagnosis, assessment and therapy control of certain renal and metabolic diseases such as acute renal failure, terminal renal disease, and metabolic status of intensive care and dialysis patients. Urea and creatinine determinations are frequently performed together in the differential diagnosis of kidney function.

Conversion factor for UREA, BUN [mg/dl]
Conc. (UREA) = 2.14 x conc. (BUN); conc. (BUN) = 0.47 x conc. (UREA)

Enzymatic colorimetric test and fully enzymatic UV test for the quantitative determination of urea in human serum, plasma and urine.
Uric acid measurements are used in the diagnosis and therapy control of numerous renal and metabolic disorders, including chronic kidney disease, kidney stones, renal failure, gout, hyperlipidemia, leukemia, psoriasis, starvation or other wasting conditions and of patients receiving cytotoxic drugs or cyclosporine therapy in transplant recipients.

Enzymatic colorimetric test with or without ascorbate oxidase for the quantitative determination of uric acid in human serum, plasma and urine.
Qualitative determination of IgG or IgM antibodies to varicella-zoster virus

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