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  2. Reagents
  3. Enzymes

Enzymes Reagents

HUMAN’s enzyme reagents deliver precision diagnostics for critical conditions, including liver diseases, myocardial infarction, pancreatic disorders, and muscle damage. Featuring enzymatic tests such as alkaline phosphatase, alpha-amylase, CK-MB, and gamma-GT, these reagents offer exceptional accuracy in quantifying enzyme activity across human serum, plasma, and urine.

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  • Enzymes

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Alkaline phosphatase activity is measured for diagnosis, monitoring and therapy control of liver, bone, parathyroid and intestinal diseases. Conditions with increased alkaline phosphatase levels are hepatobiliary diseases, primary and secondary bone diseases. Reduced alkaline phosphatase levels are found in familial hypophosphatasia, adynamic bone disease in dialysis patients, hypoparathyroidism, achondroplasia, pituitary dwarfism, chronic radiation sickness and malnutrition. Enzymatic color test for the quantitative determination of alkaline phosphatase in human serum and heparinised plasma.

Related products:  » Calibrators: Autocal   » Controls: HumaTrol N/P, Serodos   » External Quality Assessment
Alpha-amylase activity is measured for detection of acute pancreatitis, chronic (relapsing) pancreatitis, obstruction of the pancreatic duct, detection of pancreatic involvement in abdominal disorders, surgical procedures, anorexia, bulimia, and parotitis. There is also a detectable increase in amylase after an endoscopic retrograde cholangiopancreatography (ERCP) procedure.

Enzymatic color test for the quantitative determination of alpha-amylase in human serum, heparinised plasma and urine.
Cholinesterase activity measurements are used as a test of liver function in patients with acute and chronic hepatitis, liver sclerosis, as an indicator of insecticide poisoning and as a means to investigate atypical variants of the enzyme. A decreased level of enzyme activity is an indication of any of the above conditions. CHE is also used to identify patients with low enzyme activity before administration of muscle relaxants of the succinylcholine type. CHE activity is regarded as the most important indicator of degree of intoxication by organophosphorus pesticide.

Enzymatic colorimetric test for the quantitative determination of Cholinesterase in human serum and plasma.
Quantitative determination of creatine kinase-MB
Creatine kinase activity and the activity of its isoenzymes is measured for diagnosis and therapy control of myocardial infarction, myocarditis, cerebrovascular accidents, skeletal muscular dystrophies, and cardiac and skeletal muscle diseases. Creatine kinase activity is also measured for monitoring the treatment of cancer patients.

Enzymatic UV test for the quantitative determination of creatine kinase in human serum and plasma.
Gamma-GT activity measurements are used for diagnosis of suspected hepatobiliary disease, differential diagnosis and monitoring of hepatobiliary disease and monitoring of chronic alcoholism in combination with other laboratory tests.

Enzymatic color test for the quantitative determination of gamma-GT in human serum and plasma.
Aminotransferases measurements are basic investigations for the diagnosis and monitoring of liver and muscle damage. Aminotransferases are measured for diagnosis and differential diagnosis of hepatobiliary disease (GPT/ALAT), myocardial infarction (GOT/ASAT), skeletal muscle damage (GOT/ASAT), viral hepatitis (GPT/ALAT) and as a part of medical screening examinations.

Enzymatic UV test for the quantitative determination of GOT/ASAT in human serum and plasma.
Aminotransferases measurements are basic investigations for the diagnosis and monitoring of liver and muscle damage. Aminotransferases are measured for diagnosis and differential diagnosis of hepatobiliary disease (GPT/ALAT), myocardial infarction (GOT/ASAT), skeletal muscle damage (GOT/ASAT), viral hepatitis (GPT/ALAT) and as a part of medical screening examinations.

Enzymatic UV test for the quantitative determination of GPT/ALAT in human serum and plasma.
Lactate dehydrogenase measurements are used for diagnosis and therapy control of liver diseases such as acute viral hepatitis, cirrhosis, malignant liver diseases, myocardial infarction, tumors of the lung or kidneys, pulmonary embolism and hemolytic anemia.

Enzymatic UV test for the quantitative determination of lactate dehydrogenase in human serum and plasma.
Lipase activity measurements are used primarily to investigate pancreatic disorders, usually pancreatitis. Indications for lipase measurements are detection and exclusion of acute pancreatitis (in acute upper quadrant abdominal pain), chronic (relapsing) pancreatitis, obstruction of the pancreatic duct and detection of pancreatic involvement in abdominal diseases.

Enzymatic colorimetric test for the quantitative determination of lipase in human serum and plasma.
Pancreatic amylase activity measurements in serum and urine are mainly applied for the diagnosis of pancreatic disorders as well as for detecting the development of complications. As pancreatic and salivary amylase show a structural homology of 97%, the only method to distinguish is to use an assay based on monoclonal antibodies to inhibit the salivary enzyme. The amylase in the blood is eliminated through the kidneys and excreted into the urine, therefore, elevated serum activity is reflected in the rise of urinary amylase activity. For confirmation of an acute pancreatitis an additional measurement of lipase is recommended.

Enzymatic colorimetric test for the quantitative determination of pancreatic amylase in human serum, plasma and urine.

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