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Reagents

HUMAN's reagents provide high-quality and reliable solutions tailored to meet diverse laboratory needs. Our range includes multipurpose clinical chemistry assays for manual and automated testing, offering precision in the detection of enzymes, substrates/metabolites, proteins, electrolytes, and trace elements detection. Our products ensure long-term stability and high accuracy. Each reagent kit includes necessary calibrators and standards, facilitating ease of use. With a commitment to innovation, HUMAN ensures that laboratories receive efficient, cost-effective diagnostic solutions that enhance the accuracy and reliability of their results.

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  • Gastroenterology
  • Trace Elements
  • Vasculitis
  • Enzymes
  • Proteins

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Microalbuminuria is considered a clinically important indicator of deteriorating renal function in diabetic subjects and regular screening is valuable in monitoring these patients. Prospective studies have demonstrated that increased urinary albumin excretion precedes and is highly predictive of diabetic nephropathy, end stage renal disease, and proliferative retinopathy in type I diabetes. In patients with type II diabetes increased urinary albumin excretion is an independent predictor of progressive renal disease, atherosclerotic disease and cardiovascular mortality. Increased urinary albumin excretion, both independently and in conjunction with hyperinsulinemia, identifies a group of nondiabetic subjects at increased risk of coronary vascular disease.

Immunoturbidimetric test for the quantitative determination of mircoalbumin in collected urine or random midstream urine.
Quantitative determination of IgG antibodies to myeloperoxidase.
Calibration: 2.5 / 7.4 / 22.2 / 66.7 / 200 U/ml Cut-off: 10 U/ml
Pancreatic amylase activity measurements in serum and urine are mainly applied for the diagnosis of pancreatic disorders as well as for detecting the development of complications. As pancreatic and salivary amylase show a structural homology of 97%, the only method to distinguish is to use an assay based on monoclonal antibodies to inhibit the salivary enzyme. The amylase in the blood is eliminated through the kidneys and excreted into the urine, therefore, elevated serum activity is reflected in the rise of urinary amylase activity. For confirmation of an acute pancreatitis an additional measurement of lipase is recommended.

Enzymatic colorimetric test for the quantitative determination of pancreatic amylase in human serum, plasma and urine.
Quantitative determination of IgG antibodies to proteinase 3.
Calibration: 2.5 / 7.4 / 22.2 / 66.7 / 200 U/ml Cut-off: 10 U/ml
Quantitative determination of IgM antibodies to rheumatoid factor.
Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 15 IU/ml
Quantitative determination of antibodies to tissue transglutaminase.
The iron and total iron binding capacity (TIBC) levels are influenced by changes in iron intake, absorption, storage, and release mechanisms. Such changes are indicative of a wide range of dysfunctions including anemias, nephrosis, cirrhosis and hepatitis. Iron and TIBC measurements are interrelated parameters for the diagnosis of the iron status.

Saturation and absorbant reagents for sample preparation for the determination of total iron binding capacity (TIBC) in human serum or heparinised plasma.
Transferrin is the principle plasma protein for the transport of iron. Transferrin is a negative acute phase reactant and will decrease during any inflammatory state or malignancy. Increased levels of transferrin are found in iron deficiency, pregnancy, oestrogen administration and lipoidal nephrosis. Decreased levels may be encountered in hereditary deficiencies, testosterone administration, infection, acute inflammation, some forms of nephrosis, tumors, haemochromatosis, acute malaria and malnutrition.

Immunoturbidimetric test for the quantitative determination of transferrin in human serum.
The determination of total protein in urine supports the diagnosis and treatment of primary and secondary kidney disease and the diagnosis of diseases associated with cardiac and thyroid function. Increased total protein concentration in the urine (proteinuria) is a very common urinary finding and is one of the leading symptoms of kidney disease in addition to reduced eGFR.

Increased total protein concentrations in cerebrospinal fluid (CSF) are observed in a variety of disease states of the central nervous system (CNS), e.g. cerebral haemorrhage, bacterial or viral meningitis, inflammatory CNS disorders and tumors.

Colorimetric test for the quantitative determination of total protein in human urine and cerebrospinal fluid (CSF).
Qualitative determination of vasculitis IgG antibodies.

Internal function and cut-off control

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