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  2. Reagents

Reagents

HUMAN's reagents provide high-quality and reliable solutions tailored to meet diverse laboratory needs. Our range includes multipurpose clinical chemistry assays for manual and automated testing, offering precision in the detection of enzymes, substrates/metabolites, proteins, electrolytes, and trace elements detection. Our products ensure long-term stability and high accuracy. Each reagent kit includes necessary calibrators and standards, facilitating ease of use. With a commitment to innovation, HUMAN ensures that laboratories receive efficient, cost-effective diagnostic solutions that enhance the accuracy and reliability of their results.

    432 Items are shown

    Quantitative determination of total anti-HBc antibodies (anti-HBc-ab)
    Qualitative determination of antibodies to hepatitis B surface antigen (HBsAg)
    Both tests are without CE

    Qualitative determination of IgG antibodies to herpes simplex virus type 1 or 2 or IgM antibodies
    to herpes simplex virus

    Qualitative determination of the human immunodeficiency virus (HIV) p24 antigen and antibodies to HIV-1 (incl. Group O) and HIV-2

    Homocysteine is an amino acid that is formed from the metabolism of dietary proteins. Elevated levels of homocysteine are associated with a significant higher risk of cardiovascular and peripheral arterial disease. The cause of elevated levels is related to the concentration of homocysteine measured in blood and is mostly associated with renal disease, low vitamin B and/or folat intake or inborn defects in the metabolism of the essential amino acid methionine (677C>T polymorphism of MTHFR gene).

    Enzymatic UV test for the quantitative determination of homocysteine in human serum and plasma.

    Latex slide test for non-diluted serum.

    Quantitative determination of Interleukin 6

    Lyophilizied human serum-based matrix containing multi-parameter analytes for HumaCLIA SR assays To be used with : TSH, fT3, fT4, T3, T4, anti-TPO, AFP, CEA,
    CA-125, CA 19-9, CA 15-3, FSH, LH, HCG, Prolactin, Progesterone, Testosterone, Estradiol (E2), PSA*,fPSA*, 25-OH Vitamin D, PTH*, Ferritin*,
    Vitamin B12, Troponin I, CK-MB, Myoglobin

    *No CE – only for use outside Europe

    Immunoglobulins are the most important part of the humoral immune system of the organism. Of clinical interest are immunoglobulin deficiencies and increased levels of the immunoglobulins. Changes in serum immunoglobulin concentrations can be classified as follows:

    Hypogammaglobulinemias: Individuals with secretory IgA deficiency are found to suffer more commonly from mucosal infections, atopy, and autoimmune diseases. Individuals with absent IgA have a higher than expected incidence of rheumatic disorders and lymphoma.

    Polyclonal gammopathies: Increased levels occur in chronic liver disease, chronic infections, especially of the gastrointestinal and respiratory tracts, neoplasia of the lower gastrointestinal tract, inflammatory bowel disease, some immunodeficiency states such as Wiskott-Aldrich syndrome and rheumatoid arthritis.

    Monoclonal gammopathies: IgA multiple myeloma

    Immunoturbidimetric test for the quantitative determination of immunoglobulin A (IgA) in human serum
    Quantitative determination of total immunoglobulin E (IgE)
    ​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​Remark: WHO Calibration
    IgG is particularly important in the body's long-term defence against infection as it presents a slower but more sustained response than IgM to primary antigenic stimulus; however, the levels of IgG rise rapidly and early on re-exposure to the same antigenic stimulus. IgG promotes phagocytosis and activates complement. IgG is the only immunoglobulin that crosses the placenta and is therefore of special importance in the infant’s defence against infection. Changes in serum immunoglobulin concentrations can be classified as follows:

    Hypogammaglobulinemias: IgG deficiency may be genetic as in severe combined immunodeficiency or acquired as in AIDS. Definitive diagnosis requires extensive evaluation in the immune response. A decrease in IgG also occurs as a result of thermal burns, nephrotic syndrome, protein losing enteropathies and non-IgG myelomas.

    Polyclonal gammopathies: Increased levels of IgG in autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome), sarcoidosis, chronic liver disease, some parasitic diseases and chronic or recurrent infections.

    Monoclonal gammopathies: e.g. in IgG type multiple myeloma, lymphomas, leukemia, and other malignancies.

    Immunoturbidimetric test for the quantitative determination of immunoglobulin G (IgG) in human serum.
    Immunoglobulins are the most important part of the humoral immune system of the organism. The essential functions of IgM in the immune response are the agglutination of pathogens and the activation of the classical complement pathway. Elevated levels of IgM in cord serum or during the first four weeks of life may indicate intrauterine or neonatal infections such as rubella, cytomegalovirus, toxoplasmosis or syphilis. Changes in serum immunoglobulin concentrations can be classified as follows:

    Hypogammaglobulinemias: IgM deficiency is rare and is associated with recurrent pyrogenic infections.

    Polyclonal gammopathies: IgM levels are increased in primary biliary cirrhosis, haemoprotozoan infections such as malaria, viral or bacterial infections and rheumatoid arthritis.

    Monoclonal gammopathies, e.g. in Waldenström’s macroglobulinemia and malignant lymphoma.

    Immunoturbidimetric test for the quantitative determination of immunoglobulin M (IgM) in human serum.
    Hemagglutination slide test for heterophilic antibodies associated with infectious mononucleosis.
    The iron and total iron binding capacity (TIBC) levels are influenced by changes in iron intake, absorption, storage, and release mechanisms. Such changes are indicative of a wide range of dysfunctions including anemias, nephrosis, cirrhosis and hepatitis. Iron measurements are interrelated parameters for the diagnosis of the iron status.

    Colorimetric test for the quantitative determination of iron in human serum and heparinised plasma.
    Quantitative / qualitative determination of IgG antibodies to Jo-1.
    Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
    Lactate dehydrogenase measurements are used for diagnosis and therapy control of liver diseases such as acute viral hepatitis, cirrhosis, malignant liver diseases, myocardial infarction, tumors of the lung or kidneys, pulmonary embolism and hemolytic anemia.

    Enzymatic UV test for the quantitative determination of lactate dehydrogenase in human serum and plasma.
    LDL cholesterol (LDL-c) is an independent risk factor for coronary vascular disease (CHD). Epidemiological studies have shown the importance of LDL-c levels for the identification of high risk patients. HDL cholesterol (HDL-c) is regarded a protecting lipid component against coronary vascular disease (CHD). Together with HDL cholesterol LDL cholesterol has a high diagnostic value to estimate the individual risk for CHD.

    Homogeneous enzymatic color assay for the quantitative determination of LDL cholesterol in human serum and plasma.

    Quantitative determination of luteinizing hormone

    Lipase activity measurements are used primarily to investigate pancreatic disorders, usually pancreatitis. Indications for lipase measurements are detection and exclusion of acute pancreatitis (in acute upper quadrant abdominal pain), chronic (relapsing) pancreatitis, obstruction of the pancreatic duct and detection of pancreatic involvement in abdominal diseases.

    Enzymatic colorimetric test for the quantitative determination of lipase in human serum and plasma.
    Lp(a) is a risk factor for coronary vascular disease that is independent of all other lipid parameters. The Lp(a) concentration in blood varies from almost undetectable levels to more than 100 mg/dl. Differences in Lp(a) levels are genetically determined and will not be much influenced by lifestyle. The presence of high Lp(a) levels in serum is a significant marker for an increased risk of atherosclerosis and coronary vascular disease, especially when Lp(a) and LDL-c concentrations are elevated simultaneously.

    Latex enhanced immunoturbidimetric test for the quantitative determination of lipoprotein (a) in human serum.
    Qualitative determination of IgG antibodies to autoimmune liver diseases.
    Internal function and cut-off control
    Quantitative determination of IgG antibodies to liver-kidney microsomal antigen 1.

    Loopamp™ PURE DNA Extraction Kit to extract DNA from blood with heparin, blood spots on filter paper or fresh blood samples. The kit allows for 90 extractions.

    Quantitative determination of luteinizing hormone (LH)
    ​​​​​​​Remark: WHO Calibration
    Magnesium measurements are used in the diagnosis and treatment of hypo- and hypermagnesemia. When making clinical assessment of magnesium levels the calcium levels should also be considered. The best-defined manifestation of magnesium deficiency is impairment of neuromuscular function e.g. hyperirritability, tetany, convulsions, and electrocardiographic changes.

    Hypomagnesemia: Observed in diabetes, chronic alcoholism, forced diuresis, hyperthyroidism, hypoparathyroidism, hypocalcemia, malabsorption and acute pancreatitis.

    Hypermagnesemia: Increased serum magnesium levels have been found in cases of renal failure, dehydration, severe diabetic ketoacidosis and Addison's disease.

    Colorimetric test for the quantitative determination of magnesium in human serum and plasma (no EDTA plasma).

    Qualitative test for detection of Malaria Pan species (Plasmodium ovale, P. vivax, P. malariae and P. falciparum).

    Storage and shipment at 2...30°C

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